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Meridian is one of only a few manufacturers of deoxynucleoside triphosphates (dNTPs) in the world.  From the company’s foundation to the present, Meridian has been actively involved in the development and manufacture of dNTPs that meet the very highest purity standards.   

With increasing levels of sophistication of PCR processes and regulatory requirements, it has become essential to achieve the highest dNTP quality, with minimal batch-to-batch variations.  Our ultra-pure dNTPs are enzymatically synthesized from premium quality raw materials, using highly specific production systems in our purpose-built facilities. The manufacturing process eliminates impurities and PCR-specific inhibitors such as modified nucleotides, tetraphosphates and pyrophosphates commonly observed in other commercially available dNTP products.

Meridian dNTPs undergo stringent purification steps as determined by quantitative HPLC and possess ≥99% purity to enhance incorporation and yield optimal results. Consequently, Meridian ultra-high purity dNTPs are perfectly suited for a wide range of applications from PCR, including low copy number and long-range PCR, to qPCR, cDNA synthesis, site-directed mutagenesis, DNA sequencing and microarrays.

A further assurance of our dNTP quality is the ISO 13485 certification of our purpose built state-of-the-art nucleotide manufacturing facilities in Germany, demonstrating our commitment to being a reliable and technically competent partner for our customers, suppliers and future collaborators.

  • High quality – at least 99% purity determined by HPLC, ideal for use in PCR and qPCR applications
  • Optimum performance – guaranteed free from PCR inhibitors for maximum assay performance
  • Convenient formats - supplied as either individual dNTPs, sets or pre-blended dNTP mixes
  • Enzyme free - DNase, RNase and Nickase free
  • Flexible – available in custom, bulk and OEM quantities
  • Stable - extended shelf-life of 24 months at -20°C

“In our lab we only use dNTP mix from Meridian for our PCR and real-time PCR master mixtures. The quality and price are second to none! ”

Dr. Daum, Longhorn Vaccines & Diagnostics, San Antonio, USA