Bioline is one of only a few manufacturers of deoxynucleoside triphosphates (dNTPs) in the world. From the company’s foundation to the present, Bioline has been actively involved in the development and manufacture of dNTPs that meet the very highest purity standards.
With increasing levels of sophistication of PCR processes and regulatory requirements, it has become essential to achieve the highest dNTP quality, with minimal batch-to-batch variations. Our ultra-pure dNTPs are enzymatically synthesized from premium quality raw materials, using highly specific production systems in our purpose-built facilities. The manufacturing process eliminates impurities and PCR-specific inhibitors such as modified nucleotides, tetraphosphates and pyrophosphates commonly observed in other commercially available dNTP products.
Bioline dNTPs undergo stringent purification steps as determined by quantitative HPLC and possess ≥99% purity to enhance incorporation and yield optimal results. Consequently, Bioline ultra-high purity dNTPs are perfectly suited for a wide range of applications from PCR, including low copy number and long-range PCR, to qPCR, cDNA synthesis, site-directed mutagenesis, DNA sequencing and microarrays.
A further assurance of our dNTP quality is the ISO 13485 certification of our purpose built state-of-the-art nucleotide manufacturing facilities in Germany, demonstrating our commitment to being a reliable and technically competent partner for our customers, suppliers and future collaborators.